No signal until power cycle

I’ve had the AV.io 4K for about 4 years now. It goes from my main system which is running Windows to a secondary system running OBS. It is plugged into my main system all the time, the secondary system gets turned on when I use it, 2-4 times a week.

Somewhat recently (several months), it started not showing a signal to OBS, and when I investigated, I saw that the blue light right next to where the USB is plugged into it was flashing very rapidly. I unplugged it and then plugged it back in, then the blue light was steady. After deactivating and reactivating in OBS, it then works fine (yes, I did try the reactivating in OBS first).

It is running the latest firmware (4.0.0).

What would this be a symptom of?